Table 2.

Proposed methods for meeting the 5 major challenges.

Challenge	Proposed method
Variable quality of information on social media	Design a scoring method that allows selection of high-quality social media
Guarantee of data privacy	Design a technical solution based on data minimization and access restriction that guarantees data privacy of patient posting on social media
Response to pharmacovigilance expert expectations	Study the pharmacovigilance expert requirements and formalize them in use case diagrams and usage scenarios
Identification and processing of relevant information (eg, drugs and adverse drug reactions) within Web pages	Enforce best practices based on specialized dictionaries, pattern-based matching, and natural language processing to detect drugs and their adverse reactions in patient posts
Robust and evolutive architecture	Build a component-based architecture that allows storage of big data and accessibility to third-party applications through Web services