Table 2.
Association between ALL patients’ clinical and laboratorial characteristics and Stathmin 1 expressiona.
| Parameters | All patients (n = 40) |
Stathmin 1 |
p-valueb | |
|---|---|---|---|---|
| Low expression (n = 20) | High expression (n = 20) | |||
| Age; median (range), y | 27 (18–79) | 37 (18–79) | 23 (18–78) | 0.01 |
| Female; n (%) | 12 (27.9) | 8 (40) | 4 (20) | 0.17 |
| Immunophenotype | 0.43 | |||
| B-ALL (%) | 32 (80) | 17 (85) | 15 (75) | |
| T-ALL (%) | 8 (20) | 3 (15) | 5 (25) | |
| BCR-ABL1 (%) | 8 (20) | 5 (25) | 3 (15) | 0.43 |
| Hemoglobin; median, (range); g/dL | 8.7 (5.2–15.8) | 8.1 (5.3–15.8) | 8.9 (5.2–12.8) | 0.79 |
| WBC; median (range) × 109/L | 13.7 (0.8–549.5) | 8.2 (1.1–92.1) | 20.65 (0.8–549.5) | 0.06 |
| Platelets; median (range) × 109/L | 36.5 (4–433) | 38 (7–433) | 32.5 (4–162) | 0.56 |
| LDH (range) U/L | 1789 (245–13090) | 1750 (245–6848) | 1789 (270–13090) | 0.32 |
Abbreviations: ALL, acute lymphoblastic leukemia; T-ALL, precursor T-acute lymphoblastic leukemia; B-ALL, precursor B-acute lymphoblastic leukemia; BCR-ABL1, breakpoint cluster region-abelson 1; WBC, white blood cell; LDH, lactic dehydrogenase.
Statistically significant p values are highlighted in bold.
a
Patients with ALL whose sample were collected at diagnosis (n = 40) were included in association analysis.
b
Mann–Whitney test and Fisher’s exact test were used for measured and categorical factors, respectively.