Table 7.
Parameter estimates that yield best fit and comparison with estimates in literature
| Parameter | Value | Estimate of |
|---|---|---|
| Encinas et al. | ||
| Minimum number of ANP divisions | 1 | - |
| Maximum number of ANP divisions | 4 | - |
| Renewal probability of ANP | 0.1 | - |
| Expected number of ANP divisions | 1.17 | 2 |
| Expected ANP G 1-phase duration | 12hr | - |
| Minimum ANP G 1-phase duration | 3hr | - |
| Expected ANP S-phase duration | 12hr | 12hr |
| Minimum ANP S-phase duration | 4hr | - |
| Expected ANP G 2 M-phase duration | 1hr | 2hr |
| Minimum ANP G 2 M-phase duration | 0.5hr | - |
| Expected ANP-NB1 duration | 12hr | 30hr |
| Minimum ANP-NB duration | 3hr | - |
| Expected ANP-Apop2 duration | 48hr | - |
| Minimum ANP-Apop duration | 2hr | - |
| Expected NB duration | 260hr | 60hr & 306hr3 |
| Shape parameter of NB duration distribution | 2 | - |
| Minimum NB duration | 20hr | - |
| Expected apoptotic cell duration | 1.4hr | - |
| Cell death rate of ANP G 1-phase | 0.14 | - |
| Cell death rate of ANP S-phase | 0 | - |
| Cell death rate of ANP G 2 M-phase | 0.02 | - |
| Cell death rate of nonproliferating ANP | 0.33 | - |
| Cell death rate of NB | 0.97 | - |
| Minimum number of NSC divisions | 2 | - |
| Maximum number of NSC divisions | 5 | - |
| Renewal probability of NSC | 0.57 | - |
| Expected number of NSC divisions | 3.57 | 3 |
| Expected NSC G 1-phase duration | 28hr | - |
| Expected NSC S-phase duration | 11hr | 8hr |
| Expected NSC G 2 M-phase duration | 3hr | 2hr |
| Expected NSC duration | 42hr | 28hr, 28hr |
| and 52hr4 |
1ANP-NB is the transition stage between ANP and NB
2ANP-Apop is the transition stage between ANP and apoptotic cells
3NB durations for t<100h r and t>100h r, respectively
4Expected durations of the first, second and third divisions