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. 2017 Aug 18;7(8):e016248. doi: 10.1136/bmjopen-2017-016248

Table 3.

Clinical characteristics of patients with CVD (n=346)

Variables All IAH (n=33) Non-IAH (n=313) p Value
Age (years) 67 (58–78) 65 (55–73) 67 (58–78) 0.33
Male 192 (55.5) 21 (63.64) 171 (54.63) 0.322
Type of CVD 0.49
 Subarachnoid haemorrhage 93 (26.9) 11 (33.33) 82 (26.2)
 Cerebral haemorrhage 159 (46.0) 12 (36.36) 147 (46.96)
 Ischaemic stroke 94 (27.2) 10 (30.3) 84 (26.84)
Physical examination
 Body mass index (kg/m2) 21.5 (18.8–24.4) 23.7 (21.1–26) 21.3 (18.8–24.3) 0.15
 Systolic blood pressure (mm Hg) 168 (146–195) 159 (135–212) 169 (147–193) 0.93
 Pulse rate (per minute) 81 (71.5–96) 96 (81–109) 80 (71–93) <0.001
 Body temperature (°C) 36.6 (36.2–37) 36.7 (36.2–37) 36.6 (36.2–37) 0.82
 GCS score on admission 13 (10–15) 6 (4–13) 14 (11–15) <0.001
APACHE-II score on admission 11 (8–16) 18 (12–22) 10 (7–15) <0.001
Modified Rankin Scale score on admission 4 (3–5) 5 (4–5) 4 (3–5) <0.001
Favourable neurological condition* 176 (50.9) 4 (12.1) 172 (55.0) <0.001
Laboratory data on admission
 Na 142 (140–143) 142 (141–144) 142 (140–143) 0.37
 K 3.8 (3.5–4.2) 3.7 (3.3–4.1) 3.8 (3.6–4.2) 0.11
 FBS 140.5 (117–178) 152 (124–190) 138 (116–176) 0.077
 BUN 15 (12–19) 15 (12–20) 15 (12–19) 0.71
 Cr 0.74 (0.6–0.91) 0.75 (0.66–0.94) 0.74 (0.6–0.9) 0.23
Maximum sodium in ICU (mEq/L) 143 (141–145) 154 (151–156) 143 (141–145) <0.001
Minimum sodium in ICU (mEq/L) 141 (139–142) 141 (139–144) 141 (139–142) 0.29
AKI on admission 25 (7.2) 5 (15.2) 20 (6.4) 0.064
Surgery prior to ICU admission 0.047
 Elective surgery 4 (1.2) 0 (0) 4 (1.3)
 Emergency surgery 104 (30.1) 16 (48.5) 88 (28.1)
Renal replacement therapy 3 (0.9) 0 (0) 3 (1.0) 0.57
Mechanical ventilation 99 (28.6) 27 (81.8) 72 (23.0) <0.001
Length of ICU admissions (days) 4 (3–6) 8 (5–13) 4 (3–5) <0.001
Modified Rankin Scale at discharge 3 (2–4) 5 (4–6) 3 (2–4) <0.001
All-cause hospital mortality 29 (8.4) 14 (42.4) 15 (4.8) <0.001
All-cause 28-day mortality 28 (8.1) 13 (39.4) 15 (4.8) <0.001

Continuous data are median (IQR). Categorical data are n (%).

*A score of ≤3 indicates favourable neurological function.

AKI, acute kidney injury; APACHE, Acute Physiology And Chronic Health Evaluation; CVD, cerebrovascular disease; GCS, Glasgow Coma Scale; ICU, intensive care unit.