Table 3.

Subgroup analyses of the association between SSRI use and annual weight gain*

	Non-user	1–2 prescriptions/year	>2 prescriptions/year	p For interaction
Western dietary pattern				0.026
Low intake	0.00	0.11(−0.29–0.51)	0.14(−0.26–0.54)
High intake	0.00	0.46 (0.05–0.88)†	0.84 (0.43–1.24)
Prudent dietary pattern				0.635
Low intake	0.00	0.35(−0.07–0.78)	0.38(−0.02–0.78)
High intake	0.00	0.23(−0.16–0.63)	0.61 (0.20–1.02)
Physical activity				0.039
Sedentary	0.00	0.15(−0.34–0.63)	1.01 (0.52–1.50)
Low	0.00	0.34(−0.13–0.82)	0.23(−0.27–0.72)
Moderate/high	0.00	0.33(−0.27–0.94)	0.06(−0.49–0.61)
Smoking				0.002
Non-smoker	0.00	−0.28(−0.73–0.16)	0.35(−0.03–0.72)
Current or ex-smoker	0.00	0.44 (0.05–0.84)	0.66 (0.23–1.10)

*Bold values represent p<0.05.

†Models adjusted for age, gender, income, physical activity, smoking, depression status at baseline and follow-up. Stratifying variables were not adjusted in the corresponding models. Dietary pattern scores are dichotomised as low or high intake. Values represent regression coefficients (95% CI).

SSRI, selective serotonin reuptake inhibitor.