Table 2.
FibroScan® | ARFI | ELF | APRI | FIB4 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | |
cut-off | 6.5 kPa | 1.22m/s2 | 8.98 | 0.67 | 1.29 | |||||
Se | 0.71 | 0.58 - 0.83 | 0.64 | 0.43 - 0.82 | 0.83 | 0.64 - 0.94 | 0.48 | 0.35 - 0.62 | 0.68 | 0.54 - 0.8 |
Sp | 0.92 | 0.81 - 0.98 | 0.69 | 0.48 - 0.86 | 0.56 | 0.4 - 0.72 | 0.86 | 0.73 - 0.94 | 0.76 | 0.62 - 0.87 |
PPV | 0.91 | 0.79 - 0.95 | 0.67 | 0.45 - 0.84 | 0.59 | 0.42 - 0.83 | 0.79 | 0.63 - 0.87 | 0.76 | 0.62 - 0.85 |
NPV | 0.75 | 0.62 - 0.92 | 0.67 | 0.45 - 0.84 | 0.81 | 0.62 - 0.9 | 0.6 | 0.46 - 0.8 | 0.68 | 0.54 - 0.82 |
dlr.positive | 9.11 | 3.5 - 23.67 | 2.08 | 1.09 - 3.97 | 1.9 | 1.28 - 2.81 | 3.44 | 1.65 - 7.21 | 2.83 | 1.67 - 4.78 |
dlr.negative | 0.31 | 0.2 - 0.47 | 0.52 | 0.29 - 0.93 | 0.31 | 0.13 - 0.71 | 0.6 | 0.46 - 0.79 | 0.42 | 0.28 - 0.64 |
AUROC | 0.83 | 0.75 - 0.91 | 0.67 | 0.51 - 0.82 | 0.70 | 0.58 - 0.83 | 0.69 | 0.59 - 0.79 | 0.76 | 0.66 - 0.85 |
Se=sensitivity, Sp=specificity, PPV=positive predictive value, NPV=negative predictive value, dlr.positive=likelihood ratio positive, dlr.negative=likelihood ratio negative, AUROC=area under the ROC curve.