Table 3.
Statistical characteristics of advanced fibrosis (≥F3).
| FibroScan® | ARFI | ELF | APRI | FIB4 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | |
| cut-off | 7.1kPa | 1.41m/s2 | 9.47 | 0.67 | 1.22 | |||||
| Se | 0.8 | 0.59 - 0.93 | 0.57 | 0.29 - 0.82 | 0.83 | 0.52 - 0.98 | 0.6 | 0.39 - 0.79 | 0.84 | 0.64 - 0.95 |
| Sp | 0.79 | 0.69 - 0.87 | 0.84 | 0.68 - 0.94 | 0.7 | 0.56 - 0.81 | 0.77 | 0.66 - 0.85 | 0.6 | 0.49 - 0.71 |
| PPV | 0.54 | 0.41 - 0.8 | 0.57 | 0.35 - 0.82 | 0.37 | 0.25 - 0.85 | 0.44 | 0.32 - 0.66 | 0.4 | 0.29 - 0.72 |
| NPV | 0.93 | 0.83 - 0.96 | 0.84 | 0.61 - 0.94 | 0.95 | 0.81 - 0.97 | 0.86 | 0.72 - 0.92 | 0.92 | 0.81 - 0.95 |
| dlr.positive | 3.86 | 2.42 - 6.15 | 3.52 | 1.49 - 8.34 | 2.75 | 1.71 - 4.39 | 2.56 | 1.54 - 4.25 | 2.13 | 1.55 - 2.93 |
| dlr.negative | 0.25 | 0.11 - 0.56 | 0.51 | 0.27 - 0.95 | 0.24 | 0.07 - 0.86 | 0.52 | 0.32 - 0.86 | 0.26 | 0.11 - 0.66 |
| AUROC | 0.85 | 0.77 - 0.92 | 0.74 | 0.57 - 0.90 | 0.82 | 0.71 - 0.93 | 0.71 | 0.59 - 0.83 | 0.77 | 0.66 - 0.89 |
Se=sensitivity, Sp=specificity, PPV=positive predictive value, NPV=negative predictive value, dlr.positive=likelihood ratio positive, dlr.negative=likelihood ratio negative, AUROC area under the ROC curve.