Table 4.
FibroScan® | ARFI | ELF | APRI | FIB4 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | |
cut-off | 27kPa | 2.37m/s2 | 11 | 4.3 | 6.51 | |||||
Se | 1 | 0.16 - 1 | 1 | 0.16 - 1 | 0.2 | 0.25 - 0.64 | 1 | 0.16 - 1 | 1 | 0.16 - 1 |
Sp | 0.99 | 0.95 - 1 | 0.94 | 0.83 - 0.99 | 1 | 0.93 - 1 | 1 | 0.97 - 1 | 1 | 0.97 - 1 |
PPV | 0.67 | 0.26 - 1 | 0.4 | 0.18 - 1 | 1 | 0.17 - 1 | 1 | 0.35 - 1 | 1 | 0.35 - 1 |
NPV | 1 | 0.91 - 1 | 1 | 0.81 - 1 | 0.94 | 0.85 - 0.98 | 1 | 0.91 - 1 | 1 | 0.91 - 1 |
dlr.positive | 105 | 14.93 - 738.46 | 16.33 | 5.46 - 48.89 | Inf | - | I- | 0 - - | Inf | - |
dlr.negative | 0 | 0 - NaN | 0 | 0 - 1 | 0.8 | 0.80 - 1 | 0 | 0 - 1 | 0 | 0 - f |
AUROC | 0.99 | 0.98 - 1 | 0.96 | 0.90 - 1 | 0.94 | 0.91 - 1 | 1 | 1 - 1 | 1 | 1 - 1 |
Se=sensitivity, Sp=specificity, PPV=positive predictive value, NPV=negative predictive value, dlr.positive=likelihood ratio positive, dlr.negative=likelihood ratio negative, AUROC=area under the ROC curve, NaN=Null Inf=infinity.