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. 2017 Oct 5;8:54. doi: 10.1186/s13229-017-0173-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Phenotypic features in total DYRK1A sample, DYRK1A sample ascertained for ASD, and idiopathic ASD samples. Bar graph presented frequencies of core phenotypic features observed in 75% or more of DYRK1A patients. Total DYRK1A sample (Pub-SNV, UW-SNV, Pub-CHR) and DYRK1A sample ascertained for ASD were compared to frequencies of features in idiopathic ASD samples (total and IQ < 70) using Fisher’s exact tests (p < 0.001)