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. 2017 Oct 5;17:257. doi: 10.1186/s12872-017-0686-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Univariate Meta-regression Analysis of Potential Sources of Heterogeneity on Effect of ACEIs on All-Cause Mortality. Boxes and solid lines indicate RR and 95%CI, respectively for each study, and the diamonds and their width indicate the pooled RR and the 95% CI, respectively. Trials to the left of the vertical line showed a reduction in risk with the experimental intervention; those to the right showed an increase in risk with the experimental intervention. ACEI, angiotensin-converting enzyme inhibitor, MI, myocardial infraction, HF, heart failure, LVEF, left ventricular ejection fraction