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. Author manuscript; available in PMC: 2017 Oct 6.
Published in final edited form as: Nature. 1998 Jun 18;393(6686):648–659. doi: 10.1038/31405

Figure 1.

Figure 1

Overall structure. The ribbon diagram shows gp120 in red, the N-terminal two domains of CD4 in yellow, and the Fab 17b in light blue (light chain) and purple (heavy chain). The side chain of Phe43 on CD4 is shown. The prominent CDR3 loop of the 17b heavy chain is evident in this orientation. Although the complete N and C termini of gp120 are missing, the positions of the gp120 termini are consistent with the proposal that gp41, and hence the viral membrane, is located towards the top of the diagram. This would position the target membrane at the diagram base. The vertical dimension of gp120 in this orientation is roughly 50Å. Perpendicular views of gp120 are shown in Figs 2 and 4. Drawn with RIBBONS49.