Skip to main content
. 2017 Oct 6;12(10):e0184181. doi: 10.1371/journal.pone.0184181

Table 4. Description of the TNM, histological subtype and grade of the evaluable patients, excluding those TN patients.

Only pathological T and N were considered.

R0 GHR (IFR+IR+FR) p-value IFR IR FR p-value
N (%) N (%) 0.061 (T0+T1 vs T2+T3+T4) N (%) N (%) N (%)
pT (N = 6382) N = 4637 N = 1745 N = 125 N = 672 N = 948 0.146 (T0+T1 vs T2+T3+T4)
T0 (Tis) 10 (0.2) 9 (0.5) 0 2 (0.3) 7 (0.7)
T1 (49 T1mic) 2634 (56.8) 936 (53.6) 68 (54.4) 309 (46.0) 559 (59.0)
T2 1640 (35.4) 658 (37.7) 48 (38.4) 292 (43.4) 318 (33.6)
T3 158 (3.4) 66 (3.8) 6 (4.8) 40 (6.0) 20 (2.1)
T4 177 (3.8) 61 (3.5) 2 (1.6) 20 (3.0) 39 (4.1)
TX 18 (0.4) 15 (0.9) 1 (0.8) 9 (1.3) 5 (0.5)
pN (N = 6382) N = 4637 N = 1745 0.00173 (NX not anlysed) N = 125 N = 672 N = 948 0.001 (NX not anlysed)
N0 2614 (56.4) 896 (51.3) 67 (53.6) 307 (45.7) 522 (55.0)
N1 1617 (34.9) 678 (38.9) 46 (36.8) 299 (44.5) 333 (35.1)
N2 229 (4.9) 106 (6.1) 6 (4.8) 51 (7.6) 49 (5.2)
N3 76 (1.6) 24 (1.4) 4 (3.2) 7 (1.0) 13 (1.4)
NX 101 (2.2) 41 (2.3) 2 (1.6) 8 (1.2) 31 (3.3)
M (N = 7208) N = 5181 N = 2027 0.1139 (M ND not analysed) N = 144 N = 811 N = 1072 0.01383 (M ND not analysed)
M0 5020 (96.9) 1945 (96.0) 139 (96.5) 766 (94.5) 1040 (97.0)
M1 159 (3.1) 77 (3.8) 5 (3.5) 43 (5.3) 29 (2.7)
M ND 2 (0.0) 5 (0.2) 0 2 (0.2) 3 (0.3)
Grade H (N = 7208) N = 5181 N = 2027 <0.001 (GX not analysed) N = 144 N = 811 N = 1072 <0.001 (GX not analysed)
GX 912 (17.6) 399 (19.7) 26 (18.1) 168 (20.7) 205 (19.1)
G1 1128 (21.8) 324 (16.0) 19 (13.2) 88 (10.9) 217 (20.2)
G2 2134 (41.2) 760 (37.5) 49 (34.0) 303 (37.3) 408 (38.1)
G3 1007 (19.4) 544 (26.8) 50 (34.7) 252 (31.1) 242 (22.6)
Subtypes (N = 7208) N = 5181 N = 2027 0.079 (unknown not analysed) N = 144 N = 811 N = 1072 <0.001 (unknown not analysed)
Her2+ 552 (10.7) 224 (11.1) 15 (10.4) 124 (15.3) 85 (7.9)
RH+ Her2- 1452 (28.0) 499 (24.6) 36 (25.0) 200 (24.7) 263 (24.5)
Unknown 3177 (61.3) 1304 (64.3) 93 (64.6) 487 (60.0) 724 (67.6)