Table 1.
Top Ten Variants from FINEMAP Analysis of the APOE Region with Summary Statistics from the LDL-C GWAS on 15,626 Individuals and Two Sources of LD Information
|
LD Information from Original Genotype Data |
LD Information from the Finnish 1000GP Panel of 99 Individualsa |
||
|---|---|---|---|
| Variant | Posterior Probability of Being Causal | Variant | Posterior Probability of Being Causal |
| rs7412b | 1.0000 | rs7412b | 1.0000 |
| rs35136575b | 1.0000 | rs35136575b | 1.0000 |
| rs429358b | 0.8255 | rs117789739 | 1.0000 |
| rs483082 | 0.0878 | rs10418198 | 1.0000 |
| rs438811 | 0.0853 | rs75627662 | 1.0000 |
| rs2722693 | 0.0833 | rs11665929 | 1.0000 |
| rs2571177 | 0.0740 | rs141622900 | 1.0000 |
| rs2734453 | 0.0690 | rs111294029 | 1.0000 |
| rs2734457 | 0.0663 | rs61679753 | 0.9996 |
| rs12984506 | 0.0342 | rs8108277 | 0.6581 |
a
The posterior probability that rs429358 is causal is smaller than 0.0004.
b
Variants identified by a standard conditional analysis.