Distributions of LDA Scores and Probabilities of Being Dominant, P(AD), for Genes in the Training and Validation Sets
(A) Density plots of LDA score for AD (red) and AR (blue) genes of the training set. Continuous lines refer to raw values, whereas dashed lines to their normal approximations.
(B–F) Histograms of P(AD) for: (B) AD genes of the training set, (C) AR genes of the training set, (D) AD genes of the validation set, (E) AR genes of the validation set, (F) Genes known to behave as false positives in NGS experiments, containing rare, non-pathogenic variants.