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. Author manuscript; available in PMC: 2017 Oct 6.
Published in final edited form as: Cell. 2017 Aug 10;170(4):787–799.e18. doi: 10.1016/j.cell.2017.07.044

Figure 3. Unresolved R-Loops at Head-On Genes Cause Cell Death, Related to Figures S2 and S3.

Figure 3

(A and B) Survival assays for either WT, ΔrnhC, or ΔrnhC cells with rnhC expressed at an ectopic locus (ΔrnhC rnhC+) carrying the reporter gene lacZ (A) or luxABCDE (B). Top: Representative plates; bottom: quantification. CD, co-directional (black bars); HO, head-on (gray bars). Values are the means and SD in colony forming units per mL (CFU/mL) of at least four independent experiments.

(C and D) Survival assays for either WT cells or ΔrnhC cells carrying the reporter gene lacZ (C) or luxABCDE (D). Top: Representative plates; bottom: quantification. CD, co-directional (black bars); HO, head-on (gray bars). Values are the means and SD in colony forming units per mL (CFU/mL) of at least four independent experiments.