Table 2.
Variable |
Overall |
<1940 |
1940–1949 |
1950–1959 |
>1960a |
|||||
---|---|---|---|---|---|---|---|---|---|---|
HR (95% CI) | P Value | HR (95% CI) | P Value | HR (95% CI) | P Value | HR (95% CI) | P Value | HR (95% CI) | P Value | |
Age (y) | 1.11 (1.08–1.14) | <0.001 | 1.12 (1.02–1.23) | 0.02 | 1.08 (1.02–1.15) | 0.01 | 1.11 (1.07–1.16) | <0.001 | 1.02 (0.85–1.21) | 0.86 |
Sex (male vs female) | 0.81 (0.53–1.22) | 0.31 | 1.20 (0.44–3.30) | 0.72 | 0.69 (0.33–1.45) | 0.33 | 0.76 (0.40–1.46) | 0.41 | 0.1 5 (0.01–2.35) | 0.18 |
HbA1c (mmol/mol) | 1.02 (1.00–1.04) | 0.13 | 0.98 (0.94–1.03) | 0.51 | 1.04 (1.01–1.08) | 0.02 | 1.01 (0.99–1.05) | 0.24 | 0.96 (0.83–1.12) | 0.61 |
CVD (yes vs no) | 2.29 (1.50–3.49) | <0.001 | 3.55 1.08–11.6) | 0.04 | 2.52 (1.17–5.48) | 0.02 | 1.87 (0.99–3.51) | 0.05 | 0.26 (0.01–5.95) | 0.40 |
eGFR (mL/min/1.73 m2) | 0.98 (0.97–0.99) | <0.001 | 1.00 (0.97–1.03) | 0.91 | 0.98 (0.96–1.00) | 0.08 | 0.97 (0.95–0.99) | 0.001 | 0.94 (0.88–0.99) | 0.02 |
Exercise (yes vs no) | 0.54 (0.36–0.81) | 0.003 | 0.55 (0.21–1.42) | 0.22 | 0.66 (0.32–1.38) | 0.27 | 0.65 (0.32–1.30) | 0.22 | 0.36 (0.02–5.30) | 0.46 |
>1960 has four deaths.