Table 3. Positioning navigation and space exploration abilities of rats among six groups by Morris water maze experiment (n = 10).
Group | Positioning navigation (s) | Space exploration (s) |
---|---|---|
Normal group | 20.10 ± 7.15 | 33.13 ± 5.17 |
Model group | 34.25 ± 11.70* | 24.55 ± 6.34* |
Empty vector group | 35.60 ± 9.90* | 25.24 ± 5.53* |
Over-expressed lncRNA H19 group | 63.05 ± 8.30*#& | 10.37 ± 4.18*#& |
NC group | 33.68 ± 11.47* | 24.92 ± 5.17* |
LncRNA H19-shRNA group | 20.70 ± 7.02$ | 33.09 ± 4.35$ |
Notes: *, P < 0.05 as compared with the normal group; #, P < 0.05 as compared with the model group; &, P < 0.05 as compared with the empty vector group; $, P < 0.05 as compared to the NC group; lncRNA, long non-coding RNA; NC, negative group; shRNA, short hairpin RNA.