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. 2016 Jul 7;8(39):64974–64983. doi: 10.18632/oncotarget.10472

Figure 6. The down-regulation of SOX7 expression in BCP-ALL cells delays leukemogenesis initiation and spreading.

Figure 6

A. Scheme of the pGIPz lentiviral vector used to transduce the leukemia cell lines. B. Representative FACS plots of SSC and GFP expression profiles of RS4;11 human leukemia cells transduced with SOX7 shRNAs (shSOX7-2, shSOX7-3, shSOX7-2+3) and control construct (Scramble). Percentages of cells and median fluorescent intensities are shown in the indicated quadrants. FACS plots are representative of two independent experiments. C. Mice were injected intra-peritoneally with Luciferin and anesthetized before to be imaged (IVIS Lumina, Caliper Life Sciences) for 30 seconds-1 minute per side (dorsal/ventral).