Table 6. Univariate and multivariate analysis in patients with lower ESCC.
| Variable | Median survival (months) | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Sex | 0.598 | 0.310-1.154 | 0.125 | ||||
| Male | 17 | ||||||
| Female | 26 | ||||||
| Age | 1.553 | 0.934-2.582 | 0.09 | ||||
| ≥70 | 17 | ||||||
| <70 | 16 | ||||||
| T stage | 1.060 | 0.705-1.594 | 0.778 | ||||
| T1-2 | 27 | ||||||
| T3 | 14 | ||||||
| T4 | 17 | ||||||
| N stage | 2.479 | 1.742-3.529 | < 0.001*** | 2.106 | 1.447-3.064 | < 0.001*** | |
| N1 | 33 | ||||||
| N2 | 19 | ||||||
| N3 | 9 | ||||||
| TNM stage | 5.241 | 2.108-13.03 | < 0.001*** | 4.814 | 1.792-12.928 | 0.002** | |
| II | |||||||
| III | 18 | ||||||
| IV | 7 | ||||||
| Supraclavicular nodes | 1.102 | 0.679-1.787 | 0.695 | ||||
| Positive | 13 | ||||||
| Negative | 19 | ||||||
| Left gastric nodes | 1.052 | 0.648-1.710 | 0.837 | ||||
| Positive | 16 | ||||||
| Negative | 17 | ||||||
| Celiac nodes | 0.347 | 0.206-0.584 | < 0.001*** | 0.574 | 0.292-1.128 | 0.107 | |
| Positive | 11 | ||||||
| Negative | 21 | ||||||
| Common hepatic nodes | 0.264 | 0.136-0.513 | < 0.001*** | 0.377 | 0.160-0.890 | 0.026* | |
| Positive | 11 | ||||||
| Negative | 19 | ||||||
| Treatment modality | 1.502 | 0.893-2.526 | 0.126 | ||||
| Chemoradiotherapy | 17 | ||||||
| Radiotherapy alone | 17 | ||||||
| Radiation dose | 1.415 | 0.877-2.284 | 0.155 | ||||
| ≥60 Gy | 17 | ||||||
| <60 Gy | 14 | ||||||
*, P < 0.05; **, P < 0.01; ***, P < 0.001.