Table 2. Univariate analyses for prognostic variables of overall survival and disease-free survival in ESCC patients using Cox proportional-hazards regression.
| Characteristic | Overall survival | Disease–free survival | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p–value | HR | 95% CI | p–value | |
| Age (years) | 0.213 | 0.769 | ||||
| < 65 | 1.00 | – | 1.00 | – | ||
| ≥ 65 | 1.362 | 0.837–2.217 | 0.929 | 0.569–1.518 | ||
| Tumor size (cm) | 0.228 | 0.101 | ||||
| < 4 | 1.00 | – | 1.00 | – | ||
| ≥ 4 | 1.274 | 0.860–1.887 | 1.424 | 0.934–2.172 | ||
| T stage | 0.001 | 0.002 | ||||
| 1 | 1.00 | – | 1.00 | – | ||
| 2–4 | 2.536 | 1.443–4.454 | 3.011 | 1.510–6.003 | ||
| Lymph node metastasis | 0.005 | < 0.001 | ||||
| Negative | 1.00 | – | 1.00 | – | ||
| Positive | 1.767 | 1.184–2.637 | 2.655 | 1.637–4.308 | ||
| Distant metastasis | 0.049 | < 0.001 | ||||
| Negative | 1.00 | – | 1.00 | – | ||
| Positive | 1.735 | 1.003–3.001 | 2.637 | 1.566–4.441 | ||
| Twist1 in CAF | 0.003 | 0.019 | ||||
| Negative | 1.00 | – | 1.00 | – | ||
| Positive | 3.252 | 1.508–7.016 | 2.523 | 1.164–5.467 | ||