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. 2017 Jul 4;8(39):65469–65480. doi: 10.18632/oncotarget.18971

Figure 4. Knocking down SPC24 inhibits tumor growth in vivo.

Figure 4

(A) Stable SPC24- knockdown (shSPC24) cell line of PC9 was generated by shRNA, and injected subcutaneously into 6-week old immunocompromised nude mice. At time of sacrifice, tumors were collected and weighed. (B) The weights of tumors are recorded as Mean ± S.D. (n = 3) *p < 0.05 (C) IHC staining of SPC24, PARP, PCNA, and E-cadherin was performed for SPC24-knockdown (shSPC24) or control (shN) tumors.Hematoxylin and eosin (HE) staining of the tumor tissues is also shown.