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. 2017 Aug 9;8(39):65717–65729. doi: 10.18632/oncotarget.20084

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Copyright: © 2017 Li et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Effect of resveratrol and caloric restriction on mRNA expressions of SIRT1, p53 and Foxo3a in brains of aging rats. (B) Effect of resveratrol and caloric restriction on mRNA expressions of SIRT1, p53 and Foxo3a in livers of aging rats. All values were expressed as means ± SD. ^*P < 0.05, ^**P < 0.01 compared with negative control group; ^#P < 0.05, ^##P < 0.01 compared with model control group; ^#P<0.05, ^##P<0.01 compared with CR group (RES group). NG, negative control group; MG, model control group; RESL, low dose of resveratrol group; RESH, high dose of resveratrol group; CR, caloric restriction group.