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. 2017 Jul 26;8(39):65946–65956. doi: 10.18632/oncotarget.19583

Figure 1. YBX1 is involved in the glycolytic phenotype of bladder cancer cells.

Figure 1

(A) GSEA plot of glycolysis pathway based on the high-YBX1 versus low-YBX1 expression profiles. NES: normalized enrichment score; FDR: false discovery rate. (B) The mRNA and protein level of YBX1 in bladder cancer cells. (C) Summary of the glycolytic enzymes and metabolites. Glycolytic enzymes detected were highlighted in red. (D) The knockdown efficiency of YBX1 in TCCSUP and SW780 cells. (E) The effect of YBX1 knockdown on the mRNA expression of Glut1, HK2, Pfkl and Ldha. (F) The overexpression efficiency of YBX1 in T24 cells. (G) The effect of YBX1 overexpression on the mRNA expression of Glut1, HK2, Pfkl and Ldha. *, P < 0.05, **, P < 0.01.