Table 6. The predictive values of related clinical features and risk score.
| Variables | Patient N=429 | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| HR(95% CI) | P | HR(95% CI) | P | |||
| Race | White | 292 | 1(reference) | 1(reference) | ||
| Asian | 29 | 1.414(0.859-2.327) | 0.173 | 1.061(0.589-1.912) | 0.844 | |
| Gender | Female | 111 | 1(reference) | 1(reference) | ||
| Male | 311 | 1.235(0.863-1.766) | 0.249 | 2.663(1.296-5.471) | 0.008* | |
| Age | <=65 | 248 | 1(reference) | 1(reference) | ||
| >65 | 169 | 1.344(0.983-1.838) | 0.086 | 0.996(0.588-1.689) | 0.989 | |
| Tumor stage | I | 202 | 1(reference) | 1(reference) | ||
| II | 135 | 1.015(0.710-1.452) | 0.933 | 1.225(0.591-2.541) | 0.585 | |
| III | 78 | 1.610(1.106-2.343) | 0.013* | 0.474(0.181-1.242) | 0.129 | |
| IV | 7 | 3.464(1.393-8.613) | 0.007* | 0.966(0.213-4.381) | 0.964 | |
| T stage | T1 | 95 | 1(reference) | 1(reference) | ||
| T2 | 243 | 1.255(0.849-1.855) | 0.255 | 0.859(0.473-1.558) | 0.617 | |
| T3 | 63 | 1.771(1.081-2.899) | 0.023* | 1.830(0.832-4.028) | 0.133 | |
| T4 | 21 | 2.470(1.302-4.687) | 0.006* | 1.865(0.580-6.001) | 0.296 | |
| N stage | N0 | 266 | 1(reference) | 1(reference) | ||
| N1 | 116 | 1.080(0.770-1.514) | 0.656 | 1.186(0.454-3.097) | 0.728 | |
| N2 | 34 | 1.378(0.834-2.277) | 0.211 | 0.707(0.098-5.086) | 0.731 | |
| N3 | 5 | 2.713(0.665-11.067) | 0.164 | |||
| M stage | M0 | 415 | 1(reference) | |||
| M1 | 7 | 3.119(1.274-7.633) | 0.013* | |||
| Atomic neoplasm subdivision | Left lung | 179 | 1(reference) | |||
| Right lung | 220 | 1.050(0.773-1.426) | 0.754 | 0.868(0.499-1.509) | 0.617 | |
| Bronchia | 9 | 0.395(0.097-1.609) | 0.195 | 1.760(0.167-18.498) | 0.638 | |
| Primary therapy outcome | Complete remission | 259 | 1(reference) | 1(reference) | ||
| Stable disease | 14 | 3.166(1.523-6.579) | 0.002* | 2.881(0.908-9.143) | 0.073 | |
| Progressive disease | 22 | 4.901(2.876-8.351) | <0.001* | 1.778(0.829-3.814) | 0.139 | |
| Partial remission | 6 | 3.579(1.304-9.823) | 0.013* | 0.747(0.167-3.336) | 0.702 | |
| Radiotherapy | NO | 318 | 1(reference) | 1(reference) | ||
| YES | 45 | 1.427(0.915-2.225) | 0.117 | 0.818(0.321-2.084) | 0.674 | |
| Neoplasm cancer | Tumor free | 276 | 1(reference) | 1(reference) | ||
| With tumor | 87 | 4.229(2.994-5.976) | <0.001* | 3.116(1.884-5.154) | <0.001* | |
| Residual tumor | R0 | 345 | 1(reference) | 1(reference) | ||
| R1+R2 | 13 | 3.135(1.361-7.224) | 0.007* | 1.561(0.198-12.338) | 0.673 | |
| Risk score | Low | 212 | 1(reference) | 1(reference) | ||
| High | 210 | 1.815(1.341-2.456) | <0.001* | 3.116(1.884-5.154) | 0.001* | |
HR: hazard ratio; CI: confidence interval; *: P<0.05.