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. 2017 Aug 12;8(39):66328–66342. doi: 10.18632/oncotarget.20240

Table 1. Correlation between NKCC1 expression and clinical features in HCC.

Clinical features Cases NKCC1 Contingency coefficient p value
Negative Positive
Gender Male 51 16 35 0.163 0.175
Female 16 8 8
Age <60 51 19 32 0.053 0.662
≥60 16 5 11
Tumor Differentiation Poorly 26 5 21 0.266 0.024*
Well, moderate 41 19 22
Microvascular tumor thrombus Negative 42 19 23 0.247 0.037*
Positive 25 5 20
Glypican-3 Negative 8 3 5 0.013 0.916
Positive 59 21 38
Keratin 19 Negative 45 18 27 0.124 0.308
Positive 22 6 16
Ki-67 Low (<20%) 48 19 29 0.092 0.455
High (≥20%) 17 5 12

*p < 0.05 indicates a significant difference between NKCC1 expression and the clinical features, according to Chi-Square test.