Table 1. Correlation between NKCC1 expression and clinical features in HCC.
Clinical features | Cases | NKCC1 | Contingency coefficient | p value | ||
---|---|---|---|---|---|---|
Negative | Positive | |||||
Gender | Male | 51 | 16 | 35 | 0.163 | 0.175 |
Female | 16 | 8 | 8 | |||
Age | <60 | 51 | 19 | 32 | 0.053 | 0.662 |
≥60 | 16 | 5 | 11 | |||
Tumor Differentiation | Poorly | 26 | 5 | 21 | 0.266 | 0.024* |
Well, moderate | 41 | 19 | 22 | |||
Microvascular tumor thrombus | Negative | 42 | 19 | 23 | 0.247 | 0.037* |
Positive | 25 | 5 | 20 | |||
Glypican-3 | Negative | 8 | 3 | 5 | 0.013 | 0.916 |
Positive | 59 | 21 | 38 | |||
Keratin 19 | Negative | 45 | 18 | 27 | 0.124 | 0.308 |
Positive | 22 | 6 | 16 | |||
Ki-67 | Low (<20%) | 48 | 19 | 29 | 0.092 | 0.455 |
High (≥20%) | 17 | 5 | 12 |
*p < 0.05 indicates a significant difference between NKCC1 expression and the clinical features, according to Chi-Square test.