Table 1. Main characteristics of the eligible prognosis studies.

Study	Tumor type	Sample size	Test Method	Cut-off	Outcome measure	Analysis method	HR estimation	Follow-up (months)
Cao 2014	CC	102	qRT-PCR	median value	OS	Multivariate	Direct	∼60
Sun 2014	GC	89	qRT-PCR	median value	DFS, OS	Multivariate	Direct	∼40
Tu 2014	HCC	71	qRT-PCR	median value	RFS	Multivariate	Direct	∼60
Yin 2014	CRC	66	qRT-PCR	median value	OS	Multivariate	Direct	∼60
Chang 2015	HCC	50	qRT-PCR	median value	OS	Multivariate	Direct	∼60
Zhang 2015	NSCLC	50	qRT-PCR	median value	OS	Multivariate	Indirect	∼70
Hu 2016	HCC	32	qRT-PCR	median value	OS	Multivariate	Indirect	∼30
Li 2016	OC	63	qRT-PCR	median value	DFS, OS	Multivariate	Indirect	∼36
Meng 2016	GC	55	qRT-PCR	median value	OS	Multivariate	Indirect	∼ 36
Zhang 2017	BTCC	82	qRT-PCR	median value	DFS	Multivariate	Direct	∼ 60

CC: cervical cancer; GC: gastric cancer; HCC: hepatocellular carcinoma; CRC: colorectal cancer; NSCLC: non-small cell lung cancer; OC: ovarian cancer; BTCC: bladder transitional cell carcinomas; OS: overall survival; DFS: disease free survival; RFS: recurrence-free survival; HR: hazard ratio.