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. 2017 Aug 11;8(39):66476–66490. doi: 10.18632/oncotarget.20192

Table 2. The prognostic significance of SERPINB5 mRNA in gastric cancer by Kaplan-Meier plotter.

Clinicopathological features Overall survival Progression-free survival
Hazard ratio p Hazard ratio P
Sex
 Female 0.53 (0.34–0.83) 0.004 0.5 (0.31–0.81) 0.0042
 Male 0.63 (0.51–0.77) 1.4e-05 0.62 (0.49–0.78) 6.7e-05
T
 2 0.52 (0.34–0.79) 0.002 0.51 (0.33–0.78) 0.0019
 3 0.62 (0.41–0.95) 0.026 0.74 (0.53–1.04) 0.086
4 0.55 (0.21–1.46) 0.23 0.64 (0.29–1.4) 0.26
N
 0 0.41 (0.17–0.95) 0.032 0.4 (0.17–1.02) 0.048
1–3 0.58 (0.44–0.77) 9.7e-05 0.59 (0.45–0.77) 7.6e-05
 1 0.46 (0.29–0.72) 0.00047 0.47 (0.31–0.72) 0.00038
 2 0.68 (0.43–1.09) 0.11 0.69 (0.44–1.08) 0.1
 3 0.62 (0.36–1.06) 0.079 0.67 (0.39–1.16) 0.15
M
0 0.59 (0.44–0.78) 0.00027 0.6 (0.45–0.79) 0.00025
 1 1.79 (0.95–3.35) 0.067 1.71 (0.95–3.1) 0.072
TNM staging
 I 0.25 (0.07–0.88) 0.02 0.31 (0.09–1.13) 0.062
 II 0.28 (0.13–0.58) 3e-04 0.33 (0.16–0.68) 0.0014
 III 0.59 (0.44–0.8) 0.00057 0.59 (0.38–0.93) 0.021
 IV 0.64 (0.42–0.99) 0.042 0.8 (0.52–1.23) 0.31
Perforation
- 0.75 (0.47–1.18) 0.21 0.73 (0.47–1.13) 0.15
Differentiation
 Well-differentiated 0.46 (0.18–1.14) 0.086
 Moderately-differentiated 1.39 (0.73–2.66) 0.32 1.4 (0.75–2.61) 0.29
 Poorly-differentiated 0.72 (0.45–1.14) 0.16 0.72 (0.43–1.21) 0.22
Lauren’s classification
 Intestinal-type 0.55 (0.4–0.75) 0.00013 0.78 (0.55–1.11) 0.17
 Diffuse-type 0.53 (0.37–0.77) 0.00054 0.45 (0.3–0.68) 9e-05
 Mixed-type 0.38 (0.13–1.07) 0.058 0.2 (0.06–0.66) 0.0039
Her2 positivity
0.63 (0.49–0.81) 0.00039 0.6 (0.46–0.82) 0.00081
+ 0.62 (0.48–0.8) 3e-04 0.54 (0.39–0.75) 0.00016
Treatment
 Surgery alone 0.65 (0.48–0.88) 0.0044 0.62 (0.46–0.84) 0.0015
 5-FU-based adjuvant 1.63 (1.11–2.4) 0.013 1.66 (1.13–2.45) 0.0091
 Other adjuvant 0.46 (0.19–1.12) 0.079 0.5 (0.23–1.1) 0.079