Table 2. The prognostic significance of SERPINB5 mRNA in gastric cancer by Kaplan-Meier plotter.
Clinicopathological features | Overall survival | Progression-free survival | ||
---|---|---|---|---|
Hazard ratio | p | Hazard ratio | P | |
Sex | ||||
Female | 0.53 (0.34–0.83) | 0.004 | 0.5 (0.31–0.81) | 0.0042 |
Male | 0.63 (0.51–0.77) | 1.4e-05 | 0.62 (0.49–0.78) | 6.7e-05 |
T | ||||
2 | 0.52 (0.34–0.79) | 0.002 | 0.51 (0.33–0.78) | 0.0019 |
3 | 0.62 (0.41–0.95) | 0.026 | 0.74 (0.53–1.04) | 0.086 |
4 | 0.55 (0.21–1.46) | 0.23 | 0.64 (0.29–1.4) | 0.26 |
N | ||||
0 | 0.41 (0.17–0.95) | 0.032 | 0.4 (0.17–1.02) | 0.048 |
1–3 | 0.58 (0.44–0.77) | 9.7e-05 | 0.59 (0.45–0.77) | 7.6e-05 |
1 | 0.46 (0.29–0.72) | 0.00047 | 0.47 (0.31–0.72) | 0.00038 |
2 | 0.68 (0.43–1.09) | 0.11 | 0.69 (0.44–1.08) | 0.1 |
3 | 0.62 (0.36–1.06) | 0.079 | 0.67 (0.39–1.16) | 0.15 |
M | ||||
0 | 0.59 (0.44–0.78) | 0.00027 | 0.6 (0.45–0.79) | 0.00025 |
1 | 1.79 (0.95–3.35) | 0.067 | 1.71 (0.95–3.1) | 0.072 |
TNM staging | ||||
I | 0.25 (0.07–0.88) | 0.02 | 0.31 (0.09–1.13) | 0.062 |
II | 0.28 (0.13–0.58) | 3e-04 | 0.33 (0.16–0.68) | 0.0014 |
III | 0.59 (0.44–0.8) | 0.00057 | 0.59 (0.38–0.93) | 0.021 |
IV | 0.64 (0.42–0.99) | 0.042 | 0.8 (0.52–1.23) | 0.31 |
Perforation | ||||
- | 0.75 (0.47–1.18) | 0.21 | 0.73 (0.47–1.13) | 0.15 |
Differentiation | ||||
Well-differentiated | 0.46 (0.18–1.14) | 0.086 | ||
Moderately-differentiated | 1.39 (0.73–2.66) | 0.32 | 1.4 (0.75–2.61) | 0.29 |
Poorly-differentiated | 0.72 (0.45–1.14) | 0.16 | 0.72 (0.43–1.21) | 0.22 |
Lauren’s classification | ||||
Intestinal-type | 0.55 (0.4–0.75) | 0.00013 | 0.78 (0.55–1.11) | 0.17 |
Diffuse-type | 0.53 (0.37–0.77) | 0.00054 | 0.45 (0.3–0.68) | 9e-05 |
Mixed-type | 0.38 (0.13–1.07) | 0.058 | 0.2 (0.06–0.66) | 0.0039 |
Her2 positivity | ||||
− | 0.63 (0.49–0.81) | 0.00039 | 0.6 (0.46–0.82) | 0.00081 |
+ | 0.62 (0.48–0.8) | 3e-04 | 0.54 (0.39–0.75) | 0.00016 |
Treatment | ||||
Surgery alone | 0.65 (0.48–0.88) | 0.0044 | 0.62 (0.46–0.84) | 0.0015 |
5-FU-based adjuvant | 1.63 (1.11–2.4) | 0.013 | 1.66 (1.13–2.45) | 0.0091 |
Other adjuvant | 0.46 (0.19–1.12) | 0.079 | 0.5 (0.23–1.1) | 0.079 |