. Author manuscript; available in PMC: 2018 Jan 27.

Published in final edited form as: J Perinatol. 2017 Jul 27;37(10):1082–1087. doi: 10.1038/jp.2017.109

Table 3.

Independent effects (adjusted risk ratios^a) of autoimmune conditions and depression on preeclampsia.

	Number of subjects		Number of preeclampsia outcomes			Risk ratio stratified by depression status

	Exposed^b	Unexposed^b	Exposed^b	Unexposed^b	Adjusted^a risk ratio (aRR)	Adjusted^a risk ratio (aRR) in women without depression	Adjusted^a risk ratio (aRR) in women with depression

					n=2368^c	n=2144	n=224
Rheumatoid Arthritis	726	1700	42	60	1.62 (1.04, 2.53)	1.65 (1.04, 2.63)	1.08 (0.21, 5.55)
Depression					0.94 (0.48, 1.88)
					n=1991	n=1805	n=186
Crohn’s disease	347	1700	18	60	1.67 (0.93, 3.00)	1.82 (1.01, 3.30)	NE
Depression					0.56 (0.20, 1.54)
					n=1977	n=1744	n=203
Psoriasis	330	1700	21	60	1.57 (0.89, 2.77)	1.58 (0.86, 2.89)	1.39 (0.25, 7.61)
Depression					0.73 (0.33, 1.59)

Propsensity scores for adjustment include race/ethnicity, socioeconomic status, medical comorbidities, pregnancy smoking, pre-pregnancy BMI, and maternal age, and gestational age at enrollment.

Number of subjects exposed and unexposed to select autoimmune condition.

n’s represent complete case analysis.

NE=no estimate. There were no cases of preeclampsia among individuals with Crohn’s disease in the stratum with depression.