Table 2.
MIC activity of F. tularensis novicida by AGL-600
| AGL-600 | |||||
|---|---|---|---|---|---|
|
| |||||
| Antibody | 0 µM | 50 µM | 75 µM | 100 µM | |
| Streptomycin | MIC (µg/mL) | 4 | 4 | 2 | 2 |
|
|
|||||
| Fold reduction | 0 | 2 | 2 | ||
|
|
|||||
| Colistin | MIC (µg/mL) | 1024 | 512 | 512 | 512 |
|
|
|||||
| Fold reduction | 2 | 2 | 2 | ||
|
|
|||||
| Gentamicin | MIC (µg/mL) | 1 | 2 | 1 | 1 |
|
|
|||||
| Fold reduction | 0.5 | 0 | 0 | ||
|
|
|||||
| Azithromycin | MIC (µg/mL) | 2 | 1 | 1 | 0.5 |
|
|
|||||
| Fold reduction | 2 | 2 | 4 | ||
|
|
|||||
| FR 900098 | MIC (µg/mL) | 16 | 16 | 16 | 16 |
|
|
|||||
| Fold reduction | 0 | 0 | 0 | ||
|
|
|||||
| Meropenem | MIC (µg/mL) | >1024 | 32 | 16 | 8 |
|
|
|||||
| Fold reduction | 32 | 64 | 128 | ||
|
|
|||||
| Polymyxin B | MIC (µg/mL) | 1024 | 256 | 128 | 128 |
|
|
|||||
| Fold reduction | 4 | 8 | 8 | ||