Table 3.

Treatment options for HSDD (including off-label medications) [12–19]

Treatment	Indications
Flibanserin (Addyi®)	FDA-approved for generalized acquired HSDD in premenopausal women
Testosterone (oral, injectable, and transdermal)	Off-label, but increases sexual desire and satisfaction in pre- and postmenopausal women with HSDD
Bupropion (Buspar®)	Off-label, but can improve sexual function
Sildenafil (Viagra®)	Not effective for HSDD. Some improvement in FAD
Alternative therapies:  DHEA, ginkgo biloba, l-arginine	Limited data regarding effectiveness

FAD female arousal disorder, HSDD hypoactive sexual desire disorder