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CXCR2 activity of the trapped dimer. A plot showing Ca2+ release activity profiles of CXCL7 WT and trapped dimer. Measurements were carried out using differentiated HL60 cells expressing CXCR2. The EC50 values indicate that the activity of the dimer is similar to the WT. The plot shown is a representative of three independent experiments where data were collected in quadruplicate for each treatment.
