Table 2. Summary of cases of E. dermatitidis infection in children without cystic fibrosis since 1993.
No. | Age (years)/gender | Manifestation | Predisposing factor | Diagnostic method | Treatment | Outcome | Geographical region | Reference |
---|---|---|---|---|---|---|---|---|
1 | 3/M | Fungaemia | Acute leukemia | Culture | Catheter removal, AMPH-B, 5-FC | Survived | Germany | [19] |
2 | 3/M | Fungaemia | HIV infection | Culture | Catheter removal, AMPH-B, ITCZ | Survived | USA | [20] |
3 | 8/M | Systemic | None | Biopsy | AMPH-B, VRCZ | Died | Turkey | [21] |
4 | 3/M | Brain abscess, meningitis | None | Biopsy, culture, PCR | AMPH-B, FLCZ, ITLC | Died | China | [14] |
5 | 11/F | Liver cirrhosis | None | Biopsy, culture, PCR | VRCZ, liver transplantation | Survived | Korea | [22] |
6 | 17/M | Phaeohyphomycosis | None | Biopsy | ITCZ, Op | Survived | Argentina | [23] |
7 | 8/M | Brain abscess | None | Biopsy | AMPH-B, VRCZ, 5-FC | Died | China | [24] |
8 | 16/F | Pneumonia | Cystic fibrosis | Culture | ITCZ, VRCZ | ns | USA | [25] |
9 | 8/M | Pneumonia | AML after BMT | Culture | PSCZ | Died | Slovakia | Our case |
5-FC, 5-Fluorocytosine; AML, acute myeloid leukemia; AMPH-B, amphotericin B; BMT, bone marrow transplantation; F, female; FLCZ, fluconazole; ITCZ, itraconazole; M, male; ns, not stated; Op, operation; PSCZ, posaconazole; VRCZ, voriconazole.