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Spearman correlations of tortuosity ratio with variables of interest to SVD and AD in LIFE MRI (n = 53)
| ρ | P Value | |
|---|---|---|
| Age | −0.023 | .87 |
| Race | 0.202 | .15 |
| Sex | −0.304 | .03a |
| APOE4 | 0.454 | .001a |
| Pulse pressureb | 0.206 | .14 |
| VEGF | −0.236 | .096a |
| BDNF | 0.227 | .11 |
| Hemoglobin level | 0.266 | .07a |
| Physical activity—daily oderate activity (min) | −0.187 | .20 |
| 3MS | 0.199 | .15 |
Significant.
Partial correlation of pulse pressure and tortuosity ratio adjusted for antihypertensive drug use.
