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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Biol Psychiatry. 2017 Apr 7;84(11):797–802. doi: 10.1016/j.biopsych.2017.03.025

Table 2.

Results of 31P Magnetization Transfer Spectroscopy Measurements in the Human Frontal Lobe of Patients and Healthy Control Subjects

Measure BD (n=20) HC (n=28) F/t p
Metabolite ratio
 Phosphocreatine to γ-ATP 1.34 (0.16) 1.31 (0.16) 0.151 0.700
 Inorganic phosphate to γ-ATP 0.38 (0.08) 0.39 (0.07) 0.044 0.835
 Phosphodiester to γ-ATP 0.76 (0.13) 0.86 (0.19) 4.500 0.038
 Phosphomonoester to γ-ATP 1.09 (0.14) 1.06 (0.13) 0.682 0.413
Intracellular pH 7.02 (0.02) 7.02 (0.02) 0.097 0.757
Rate constant kf of creatine kinase, s−1 0.21 (0.05) 0.24 (0.04) 4.990 0.031
Flux of creatine kinase, μmol/g/min 46.06 (12.8) 51.87 (12.62) 4.402 0.042
Magnesium ion concentration, mmol/L 0.16 (0.03) 0.16 (0.03) 0.154 0.698

All measures presented as mean (SD)