Table 1.
Seven Promising Candidate Genes with Strong Signatures of Selection and Their Associated Phenotypes and GO Terms
| Associated Phenotype | Gene | Z(Fst) | Z(H) | Chr | Associated GO Terms |
|---|---|---|---|---|---|
| Developmental processes | TBX19 | 17.97 | −3.52 | 4 | Anatomical structure morphogenesis (GO: 0009653); pituitary gland development (GO: 0021983); regulation of cell proliferation (GO: 0042127); cell fate commitment (GO: 0045165); regulation of cell differentiation (GO: 0045595) |
| Fertility | AHR | 13.58 | −2.98 | 9 | Xenobiotic metabolic process (GO: 0006805); apoptotic process (GO: 0006915); cell cycle (GO: 0007049); reproductive structure development (GO: 0048608); gland development (GO: 0048732); metabolic process (GO: 0008152) |
| Muscle growth | MSTN | 11.40 | −3.42 | 15 | Transforming growth factor beta receptor signaling pathway (GO: 0007179); muscle organ development (GO: 0007517); response to heat (GO: 0009408); skeletal muscle tissue regeneration (GO: 0043403); negative regulation of myoblast differentiation (GO: 0045662); negative regulation of insulin receptor signaling pathway (GO: 0046627); cell development (GO: 0048468); negative regulation of skeletal muscle satellite cell proliferation (GO: 1902723); negative regulation of satellite cell differentiation (GO: 1902725); negative regulation of myoblast proliferation (GO: 2000818); growth (GO: 0040007) |
| Nervous system | P2RY1 | 9.87 | −2.96 | 13 | Eating behavior (GO: 0042755)response to growth factor (GO: 0070848); cellular response to organic cyclic compound (GO: 0071407); protein localization to plasma membrane (GO: 0072659); relaxation of muscle (GO: 0090075); signal transduction (GO: 0007165); hemostasis (GO: 0007599) |
| Olfaction | OR14A16 | 8.12 | −3.88 | 2 | G-protein coupled receptor signaling pathway (GO: 0007186); detection of chemical stimulus involved in sensory perception of smell (GO: 0050911); signal transduction (GO: 0007165); sensory perception of smell (GO: 0007608) |
| Olfaction | OR11L1 | 7.69 | −2.99 | 2 | Detection of chemical stimulus involved in sensory perception of smell (GO: 0050911); sensory perception of smell (GO: 0007608); response to stimulus (GO: 0050896) |
| Immune system | MARCH1 | 10.24 | −3.48 | 8 | Antigen processing and presentation of peptide antigen via MHC class II (GO: 0002495); immune response (GO: 0006955); immune system process (GO: 0002376) |