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. 2017 May 13;435(1):193–196. doi: 10.1007/s11010-017-3068-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — a MIC values for CX-4945 against S. cerevisiae strains, b Macroscopic view of the growth of different S. cerevisiae strains. After the MIC assay, the cells from appropriate wells corresponding to MIC, 2 × MIC, and 4 × MIC, were cultured on SDA medium. c Macroscopic view of C. albicans colonies grown on agar medium supplemented with FSB (hyphal inductor) and DMSO (control) or CX-4945. d Effect of CX-4945 on biofilm formation of Candida cells. The black bars indicate the influence of the compound on the adhesion phase during biofilm formation and the gray bars reflect the influence of CX-4945 on established, mature biofilm. Farnesol was used as a positive control