Table 5.
Comparison of upper GI endoscopic findings in the headache groups and controls.
Migraine (N = 168) |
TTH (N = 168) |
Control (N = 336) |
p-Value1 | p-Value2 | ||||
---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | |||
Esophagus | 0.43530 | 0.7099 | ||||||
Normal | 57 | 33.93 | 63 | 37.50 | 136 | 40.48 | ||
Reflux esophagitis | 103 | 61.31 | 98 | 58.33 | 185 | 55.06 | ||
Miscellaneous | 8 | 4.76 | 7 | 4.17 | 15 | 4.46 | ||
Stomacha,b | <0.0001 | 0.0003 | ||||||
Normal | 1 | 0.60 | 0 | 0.00 | 3 | 0.89 | ||
CSG | 126 | 75.00 | 137 | 81.55 | 246 | 73.21 | ||
Erosive gastritis | 29 | 17.26 | 20 | 11.90 | 46 | 13.69 | ||
Ulcers | 10 | 5.95 | 10 | 5.95 | 11 | 3.27 | ||
Miscellaneous | 2 | 1.19 | 1 | 0.60 | 30 | 8.93 | ||
Duodenum | 0.7232 | 0.7059 | ||||||
Normal | 142 | 84.52 | 150 | 89.29 | 283 | 84.23 | ||
Duodenitis | 5 | 2.98 | 2 | 1.19 | 7 | 2.08 | ||
Ulcer | 20 | 11.90 | 14 | 8.33 | 41 | 12.20 | ||
Miscellaneous | 1 | 0.60 | 2 | 1.19 | 5 | 1.49 | ||
Reflux esophagitis severity (Los Angeles classification) | 0.2650 | 0.4851 | ||||||
LA-M | 84 | 81.55 | 77 | 78.57 | 157 | 84.86 | ||
LA-A | 14 | 13.59 | 15 | 15.31 | 23 | 12.43 | ||
LA-B | 4 | 3.88 | 6 | 6.12 | 4 | 2.16 | ||
LA-C | 0 | 0.00 | 0 | 0.00 | 1 | 0.54 | ||
LA-D | 1 | 0.97 | 0 | 0.00 | 0 | 0.00 | ||
Gastritis severityc | 0.0003 | 0.0002 | ||||||
Mild | 69 | 54.76 | 55 | 40.15 | 160 | 65.04 | ||
Moderate | 52 | 41.27 | 74 | 54.01 | 78 | 31.71 | ||
Severe | 5 | 3.97 | 8 | 5.84 | 8 | 3.25 |
p-Value1, headache group vs. control group.
p-Value2, migraine group vs. TTH groups vs. control group.
GI, gastrointestinal; TTH, tension-type headache; CSG, chronic superficial gastritis.
aSignificant differences between the migraine and control groups by multiple comparisons using Bonferroni correction (p = 0.0071).
bSignificant differences between the TTH group and controls by multiple comparisons using Bonferroni correction (p = 0.0007).
cSignificant differences between the TTH and control groups by multiple comparisons using Bonferroni correction (p < 0.0001).