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. 2017 Oct 3;8:526. doi: 10.3389/fneur.2017.00526

Table 5.

Comparison of upper GI endoscopic findings in the headache groups and controls.

Migraine (N = 168)
TTH (N = 168)
Control (N = 336)
p-Value1 p-Value2
N % N % N %
Esophagus 0.43530 0.7099
Normal 57 33.93 63 37.50 136 40.48
Reflux esophagitis 103 61.31 98 58.33 185 55.06
Miscellaneous 8 4.76 7 4.17 15 4.46
Stomacha,b <0.0001 0.0003
Normal 1 0.60 0 0.00 3 0.89
CSG 126 75.00 137 81.55 246 73.21
Erosive gastritis 29 17.26 20 11.90 46 13.69
Ulcers 10 5.95 10 5.95 11 3.27
Miscellaneous 2 1.19 1 0.60 30 8.93
Duodenum 0.7232 0.7059
Normal 142 84.52 150 89.29 283 84.23
Duodenitis 5 2.98 2 1.19 7 2.08
Ulcer 20 11.90 14 8.33 41 12.20
Miscellaneous 1 0.60 2 1.19 5 1.49
Reflux esophagitis severity (Los Angeles classification) 0.2650 0.4851
LA-M 84 81.55 77 78.57 157 84.86
LA-A 14 13.59 15 15.31 23 12.43
LA-B 4 3.88 6 6.12 4 2.16
LA-C 0 0.00 0 0.00 1 0.54
LA-D 1 0.97 0 0.00 0 0.00
Gastritis severityc 0.0003 0.0002
Mild 69 54.76 55 40.15 160 65.04
Moderate 52 41.27 74 54.01 78 31.71
Severe 5 3.97 8 5.84 8 3.25

p-Value1, headache group vs. control group.

p-Value2, migraine group vs. TTH groups vs. control group.

GI, gastrointestinal; TTH, tension-type headache; CSG, chronic superficial gastritis.

aSignificant differences between the migraine and control groups by multiple comparisons using Bonferroni correction (p = 0.0071).

bSignificant differences between the TTH group and controls by multiple comparisons using Bonferroni correction (p = 0.0007).

cSignificant differences between the TTH and control groups by multiple comparisons using Bonferroni correction (p < 0.0001).

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