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OPN polarizes astrocytes towards the infarct. (a) Infarct margin stained for GFAP showing the majority of astrocytes with processes aligned towards the infarct core in OPN-treated animals, and increased process length in OPN-treated animals. Quantification of changes in polarisation (b) and process length (c). All graphs show mean and SD. ∗p < 0.05; ∗∗∗p < 0.001.
