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. 2017 Jun 27;14(5):507–517. doi: 10.1177/1740774517716937

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — The expected sample size curves of several sequential SW-CRT designs with different possible choices for $T$ in (a) Scenario 1 and (b) Scenario 2, along with that of the corresponding classical SW-CRT design ( $T = {5}$ in Scenario 1 and $T = {9}$ in Scenario 2), are displayed. Early stopping is allowed for efficacy and futility, with $γ_{e} = γ_{f} = 0.5$ .