Table 1.
Reactivity and specificity of the non-Hib serotyping LAMP assay.
| Organism | Number of strains | Origin of isolatea | Capsule typeb | Non-Hib serotyping LAMP assay |
||||
|---|---|---|---|---|---|---|---|---|
| a | c | d | e | f | ||||
| Standard H. influenzae strains (n = 8)d | 1 | — | a | +c | - | - | - | - |
| 1 | — | b | - | - | - | - | - | |
| 1 | — | c | - | + | - | - | - | |
| 1 | — | d | - | - | + | - | - | |
| 1 | — | e | - | - | - | + | - | |
| 1 | — | f | - | - | - | - | + | |
| 2 | — | nt | - | - | - | - | - | |
| Reference H. influenzae strains (n = 34)e | 5 | RT | a | + | - | - | - | - |
| 8 | CSF | b | - | - | - | - | - | |
| 4 | CSF | c | - | + | - | - | - | |
| 1 | — | d | - | - | + | - | - | |
| 3 | — | e | - | - | - | + | - | |
| 1 | CSF | f | - | - | - | - | + | |
| 6 | RT | f | - | - | - | - | + | |
| 6 | RT | nt | - | - | - | - | - | |
aRT, respiratory tract specimen; CSF, cerebrospinal fluid. bCapsule types were confirmed by H. influenzae serotyping PCR (Falla et al., 1994). nt, non-typeable. c+, positive, amplification after a 35min incubation; -, negative, no amplification after a 60 min incubation. dSource: Institute of Medical Science, University of Tokyo, Tokyo, Japan. eProvided by Prof. Emeritus Mogens Kilian, Biomedicine, Aarhus University, Aarhus, Denmark.