Fig. 2.

Fecal bacterial loads over time following peroral MDR P. aeruginosa association of secondary abiotic mice. Secondary abiotic mice (antibiotic treatment withdrawn 3 days prior infection) were perorally associated with a murine commensal E. coli (Ecol, white circles) or a multidrug resistant P. aeruginosa strain (Psae, black circles) on day (d) 0. Intestinal colonization densities were determined in fecal samples over time until day 28 postinfection (p.i.) by culture and expressed as colony forming units per gram (CFU/g). Numbers of mice, medians (black bars), and significance levels (p values) determined by Mann–Whitney U test are indicated. Data shown were pooled from two independent experiments