Figure 2.

Multicellular one-dimensional (1D) and 2D tissue models. (A) A 1D transmural ventricular cable of 24.75 mm which contains 9 mm long endocardial region (ENDO), 6.75 mm long midmyocardial region (MCELL) and 9 mm long epicardial region (EPI). The S1 stimulus is applied to a 0.45 mm ENDO region. (B) A 1D homogeneous ventricular cable of 24.75 mm with MCELL cells is constructed and the S1 stimulus is applied to a 0.45 mm region at the end of the cable. (C) A 2D transmural ventricular model was constructed by expanding the 1D transmural fiber into a sheet with a length of 150 mm and a width of 24.75 mm. The S1-S1 stimulation is applied to the 0.45 × 75 mm² region at the left side of the ENDO layer. (D) A 375 × 375 mm² homogeneous tissue with MCELL cells was developed. Location of S1stimulation (Red) and region of S2 stimulation (Blue) are shown.