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. 2017 Sep 11;199(8):2777–2793. doi: 10.4049/jimmunol.1601711

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Copyright © 2017 by The American Association of Immunologists, Inc.

This article is distributed under The American Association of Immunologists, Inc., Reuse Terms and Conditions for Author Choice articles.

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FIGURE 2. — Surface phenotype of progeny generated from total HPCs in the presence or absence of Notch signaling. Representative flow histograms of ILC3 and cNK cell surface markers in progeny generated from PB total HPCs under (−)NL/(−)IL-7(+)IL-15, (+)NL/(+)IL-7(−)IL-15, and (+)NL/(+)IL-7(+)IL-15 conditions for 4.5 wk, as shown in Fig. 1A. IL-15 was added to the culture from the beginning under (+)NL/(+)IL-7(+)IL-15 conditions. Each histogram was obtained by gating for CD56⁺CD11a⁻ and CD56⁺CD11a⁺ fractions of the progeny population. Similar results were obtained for the other two donors.