Table I. Genes regulated by the PMA and TNF treatment.
TNF Fold Change | PMA Fold Change | |
---|---|---|
MIR146A | 40.5 | 46.1 |
WNT10A | 30.9 | 11.5 |
CHRNA6 | 25.1 | 3.0 |
CCL1 | 17.3 | 11.9 |
BIRC3 | 16.2 | 14.9 |
BCL3 | 16.1 | 15.7 |
RELB | 14.7 | 16.5 |
IL-4I1 | 13.9 | 11.7 |
NFKBIA | 13.1 | 5.8 |
LTB | 11.9 | 46.1 |
KREMEN2 | 8.2 | 4.2 |
NFKB2 | 8.0 | 6.8 |
PGLYRP4 | 7.7 | 17.2 |
RGS16 | 7.3 | 26.8 |
GATA3-AS1 | 7.3 | 16.4 |
EPHA2 | 6.8 | 6.7 |
IER3 | 6.5 | 92.8 |
TTC40 | 6.2 | 4.2 |
TNFSF10 | 5.8 | 6.4 |
NINJ1 | 5.7 | 7.7 |
TNFAIP3 | 5.7 | 7.3 |
SGK1 | 5.6 | 23.6 |
FCGBP | 5.6 | 3.9 |
CYTH4 | 5.6 | 8.2 |
PRR9 | 5.4 | 21.7 |
TNFRSF18 | 5.3 | 25.6 |
TRAF4 | 5.1 | 5.9 |
PGLYRP3 | 5.1 | 6.5 |
Subset of 28 of the 36 genes induced at least 5-fold by TNF, which are also induced at least 2-fold by PMA, showing the fold induction in Jurkat T cells compared with nonstimulated cells. This list includes 24 genes induced at least 5-fold by PMA. Jurkat cells were stimulated with 30 ng/ml TNF for 3 h.