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. 2017 Sep 25;2017:6592139. doi: 10.1155/2017/6592139

Table 1.

Applications Population/Animal models Radioligand Main findings Ref.
Preclinical (i) TSPO PET on day 8 after DSS- and TNBS-induced IBD in rats
(ii) 6 rats were followed up over 22 days
18F-DPA-714 (i) Significantly increased tracer uptake in the rat colon in both groups, DSS and TNBS, compared to controls
(ii) Increased tracer binding until day 8/10 then tracer uptake decreased slowly
Bernards et al. (2014) [25]

DSS, dextran sodium sulfate; IBD, inflammatory bowel disease; TNBS, trinitrobenzenesulfonic acid.