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. 2017 Sep 24;2017:8370593. doi: 10.1155/2017/8370593

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Copyright © 2017 Hai-han Liao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Myricetin promoted the production of Nrf2 downstream genes and inhibited the expression of 4-HEN in vivo. (a) Representative blots of heme oxygenase 1 (HO-1) and GAPDH (n = 6). (b) Histogram presented the calculation of Western blots of HO-1 (n = 6). (c), (d), and (e) The relative mRNA expression of NQO1, SOD1, and SOD2 (n = 4). (f) Representative blots showed the expression of 4-hydroxynonenal (4-HEN). (g) Histogram presented the calculation of Western blots of 4-HEN; all of the proteins and mRNA expression were normalized to GAPDH before relative quantitative analysis. Data were presented as means ± SEM. ^∗P < 0.05 versus CON and ^#P < 0.05 as compared with STZ group.