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. Author manuscript; available in PMC: 2017 Oct 9.
Published in final edited form as: Adv Exp Med Biol. 2009;611:537–538. doi: 10.1007/978-0-387-73657-0_235

Table 1.

Binding affinities.

Peptide Binding affinities Functional assay
Ki(nM) IC50 (nM) (agonist) Ke (nM)
hDOR rMOR rNK1 MVD GPI SP(GPI) (antagonist)
NP30 4.7 0.29 4.2 21 26 59
NP32 58 11 1.6 13 430 250
NP34 25 2.2 7.4 68 200 0.96
NP40 3.9 2.8 2.4 58 530 610