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. 2017 Sep 27;13(9):e1006576. doi: 10.1371/journal.ppat.1006576

Fig 1. Malaria-associated atypical MBCs upregulate TBX21.

Fig 1

(A) Principal components analysis of gene expression of selected regulators of B and T cell differentiation (selected genes shown in B) in naïve B cells (CD19+CD21+CD27−; green), classical MBCs (CD19+CD21+CD27+; pink) and atypical MBCs (CD19+CD21−CD27−; purple). (B) Ex vivo RMA-normalized log2 gene expression values of selected regulators of B and T cell differentiation (rows) for each subject (columns; n = 20) within each B cell subpopulation. Differentially expressed genes in atypical MBCs relative to classical MBCs are indicated with an asterisk.