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. 2017 Sep 27;13(9):e1006589. doi: 10.1371/journal.ppat.1006589

Fig 8. CHOP-/- mice are resistant to Hc infection.

Fig 8

(A) C57BL/6 and CHOP-/- mice were mock infected (uninf) or infected with 1x106 Hc yeast and the percentage of apoptotic (viability dye+ and caspase-3/7+) alveolar macrophages (CD45+ SiglecF+ CD11bmid CD11c+ F4/80+) was measured at 3 dpi. *p<0.05, as determined by ANOVA. (B) CFUs from lungs and spleens of C57BL/6 and CHOP-/- mice infected with 3 x 105 Hc yeast. *p<0.05, **p<0.005, as determined by independent 1-way ANOVA analyses of log transformed CFUs at each time point. (C) Kaplan-Meier survival curves of C57BL/6 and CHOP-/- mice mock infected (uninf; n = 2) or infected with 1 x 106 Hc yeast (n = 11). *p<0.05, logrank test.