Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 3;10:4809–4819. doi: 10.2147/OTT.S140886

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Li et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Constitutive activity RhoA and Rac1 rescue the migration and invasion of TNBC cells inhibited by kaempferol.

Notes: (A–C) MDA-MB-231 TNBC cells were transfected with constitutive activity RhoA (RhoA-V14) or vector, then subjected to the RhoA activity assays (A), wound healing assays (B), and cell invasion assays (C). (D–F) MDA-MB-453 TNBC cells were transfected with constitutive activity Rac1 (Rac1-V12) or vector, then subjected to the Rac1 activity assays (D), wound healing assays (E) and cell invasion assays (F). The relative levels of Rho activity and cell migration distance were normalized to the average value of controls. Results are presented as mean ± SD of 3 independent experiments in (A, C, D, F) and 5 independent experiments in (B, E).

Abbreviations: Ctrl, control; TNBC, triple-negative breast cancer.